Huberman Lab

Essentials: Using Your Nervous System to Enhance Your Immune System

845 snips
Sep 25, 2025
The discussion delves into the intricate connection between the immune and nervous systems. You'll learn about the three layers of immune defense and get practical tips for enhancing immune function through breathing techniques and sleep positioning. Explore how mindset can influence healing, as well as the role of the vagus nerve in signaling infections. Discover intriguing methods like cyclic hyperventilation that can boost immunity, and the benefits of integrating fermented foods into your diet. It's a fascinating look at how our bodies defend and recover.
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INSIGHT

Three-Layer Immune Architecture

  • The immune system has three layered defenses: skin, mucus-lined openings, then innate and adaptive responses.
  • These layers act sequentially to block, rapidly attack, and then specifically remember invaders.
ADVICE

Protect Mucus With Nasal Breathing And Ferments

  • Maintain healthy mucus and microbiomes by nasal breathing, avoiding touching your eyes, and eating fermented foods.
  • Aim for two to four servings daily of low-sugar fermented foods like sauerkraut, kimchi, or natto to support mucus health.
INSIGHT

Sickness Behavior Is Purposeful

  • Sickness behavior (lethargy, loss of grooming, photophobia) is a motivated state driven by vagus signaling to the hypothalamus.
  • That signaling promotes fever and rest to optimize recovery rather than being mere malaise.
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