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As individuals age, hormonal changes such as decreased estrogen and progesterone in women, and increased luteinizing hormone and follicle stimulating hormone in men, can have a significant effect on muscle health. The decrease in estrogen during menopause can lead to muscle loss and sagging skin, affecting connective tissue and collagen. Progesterone, which protects against neurodegeneration, decreases in both men and women as they age. Cholesterol plays a crucial role in muscle-building as it is a raw material for synthesizing steroid hormones like testosterone. Decreased melatonin levels, which protect mitochondria in muscles, can affect sleep and muscle regeneration. Increasing melatonin through exposure to infrared light can be beneficial.