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The Jordan Harbinger Show

1005: David Fajgenbaum | Leveraging AI to Cure Rare Diseases

Jun 18, 2024
David Fajgenbaum, author of 'Chasing My Cure' and founder of Every Cure, shares his compelling journey fighting Castleman disease and how he turned his experiences into a mission to help others. He discusses the inefficiencies in the healthcare system that hinder the discovery of treatments for rare diseases. Fajgenbaum explains how AI can be leveraged to match existing FDA-approved drugs with rare conditions, providing hope for patients. His innovative nonprofit aims to revolutionize drug repurposing, making a significant impact in the world of rare disease research.
01:17:24

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Quick takeaways

  • Existing drugs can be repurposed for treating rare diseases through AI algorithms.
  • Pharmaceutical companies lack incentives to explore drugs for rare diseases.

Deep dives

Discovered the Sleeper Drug for Calciman's

After facing multiple near-death experiences due to Calciman's disease, the speaker dives into a relentless quest to find a suitable treatment. Experimenting with a drug called sirolimus, initially used for organ transplant rejection and treating rare lung diseases, proves to be the breakthrough. Self-testing the drug and embarking on a process of self-discovery, the speaker enters a phase of remission that extends over a decade, defying the odds and finding hope in everyday victories.

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