Episode 141: Myeloma Series, Pt.2 - Intro to MGUS and Smoldering Myeloma (2025)

In today’s episode, we continue our myeloma series, this time we’ll delve deeper into the spectrum of plasma cell dyscrasias, including defining MGUS, discussing surveillance of MGUS, defining smoldering myeloma (SM). We are slowly inching our discussion towards the diagnosis of Multiple myeloma (MM)!

Content:

- Defining MGUS

- Discussing risk of progression of MGUS to MM

- How to interpret free light chains in renal failure

- How do we monitor MGUS patients?

- When do we do additional testing in MGUS?

- What is smoldering myeloma?

- What are myeloma defining events?

- How do we risk stratify SM patients?

- How do we monitor SM patients?

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