

The Mitochondria Enhancement Debate! - with Alex Kikel and Anthony Castore
TOP TAKEAWAYS:
- Why combining BAM15 + SLU-PP-332 could be sabotaging your results
- The "start low, go slow" protocol that prevents mitochondrial damage
- How to structure fasting + refeed cycles for maximum fat loss
- Advanced supplementation strategies for 40+ professionals
- The critical difference between structure and function optimization
In this landmark 2-hour debate, mitochondrial experts Anthony Castore and Alex Kikel dive deep into the controversial combination of BAM15 and SLU-PP-332. This isn't your typical supplement discussion – it's a masterclass in advanced optimization for experienced athletes and high-performing professionals.
This episode breaks down the complex world of mitochondrial enhancement, covering everything from basic cellular structure to cutting-edge peptide protocols. Anthony and Alex present different perspectives on combining these powerful compounds, with one advocating for separation and strategic timing, while the other supports careful low-dose combination approaches.
CHAPTER BREAKDOWN:
- Mitochondrial Membrane Potential & Hyperpolarization
- The Structure-Function Relationship in Cellular Optimization
- BAM15: Uncoupling for Fat Loss and Cognitive Enhancement
- SLU-PP-332: PGC1-Alpha Activation and Mitochondrial Biogenesis
- Combination Protocols: Benefits vs. Risks
- Advanced Fasting + Refeed Strategies
- Supporting Supplement Stacks for Maximum Safety
- Real-World Application for Different Populations
KEY PROTOCOLS DISCUSSED:
- 24-hour fast to refeed optimization sequence
- Training day vs. rest day compound timing
- Dosage titration strategies (100mcg-50mg ranges)
- Biomarker tracking for safety monitoring
- Polypharmacy considerations for TRT users
IMPORTANT DISCLAIMER: This content is for educational purposes only. These are research compounds without human safety studies. Always consult healthcare professionals before implementing any protocols discussed.