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The Fellow on Call: The Heme/Onc Podcast

Episode 091: Heme Consult Series: Intro to Acquired Hemolytic Anemia and G6PD Deficiency

Feb 6, 2024
The podcast discusses hemolytic anemias, including the workup for acquired hemolytic anemias and G6PD deficiency. They cover when to suspect these conditions and the importance of tailored clinical assessment and management strategies.
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Quick takeaways

  • Recognizing symptoms of hemolysis like jaundice and dark urine is crucial for diagnosing hemolytic anemias.
  • Understanding the complexity of G6PD deficiency, its severity range, and triggers assists in effective patient management.

Deep dives

Understanding Hemolytic Anemias

Hemolytic anemias are crucial for hematologists to grasp, often presenting as unexplained acute anemia associated with homolysis, the breakdown of red blood cells. Symptoms indicating homolysis include jaundice, dark urine, and abdominal pain. Key considerations for diagnosis involve evaluating the patient's history, recent medications, illnesses, and family history of anemia. Laboratory tests like CBC, reticulocyte count, LDH, and the direct antiglobulin test (DAT) play a significant role in confirming hemolytic anemias.

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