The hosts announce the final episode and discuss personal relationships. They engage in banter, share anecdotes, and talk about inappropriate conduct by dentists and doctors. They introduce Mark Proch, talk about their role in a new Muppets show, and discuss inclusivity. They try to pronounce Mark's last name and address rumors about the Muppet show. They discuss love, laughter, and Dick Cheney, and share experiences before 9-11. They talk about faking migraines and lying for fake sick days. They make phone calls to confused deli employees and discuss a dangerous birth control drug.