
The Adversity Advantage with Doug Bopst Lung Doctor: How Vaping Silently Damages Your Lungs & What You Can Do To Quit For Good | Dr. Frank Leone
Oct 23, 2025
Dr. Frank Leone, a Professor at the University of Pennsylvania and expert in tobacco dependence, joins to discuss the alarming truths about vaping. He reveals that vaping is not safer than cigarettes and outlines how its aerosols damage lungs and heart. Dr. Leone explains nicotine's addictive nature and the intense withdrawal symptoms that many face. He's got strategies for quitting, focusing on support, empathy, and skill-building. The conversation emphasizes the importance of addressing vaping's impact on mental health and relationships.
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Vaping's Harm Depends On More Than Chemicals
- Vaping isn't just about fewer carcinogens; particle size, temperature, and user patterns shape harm.
- Dual use of vapes and cigarettes can increase lung and heart damage versus using one product only.
Vaping Causes Oxidative Stress Beyond Cancer Risk
- Vape aerosols cause oxidative stress that affects heart and vascular function even in first-time users.
- Reduced lung cancer risk doesn't eliminate cardiovascular and inflammatory harms from vaping.
‘Popcorn Lung’ Was A Real Early Risk
- Diacetyl in early vape liquids caused 'popcorn lung' in factory workers and was present in early devices.
- Newer disposable devices reduced diacetyl concerns but overall inflammatory effects remain worrying.

