The Gillett Health Podcast What everyone misses about Methylene Blue
Aug 4, 2025
Dive into the intriguing world of methylene blue, where its potential as a performance enhancer and medical aid takes center stage. Explore how it may assist those tapering off SSRIs, alongside its nootropic claims. Discover its mood-boosting abilities and cognitive benefits, but also the risks that come with it. The discussion emphasizes the critical need for clinical evidence and professional consultation, all wrapped in a light-hearted approach to self-medication pitfalls.
AI Snips
Chapters
Transcript
Episode notes
Methylene Blue's Serotonin Impact
- Methylene blue has significant serotonin-related effects as a MAO-A inhibitor, potentially causing serotonin syndrome.
- It is less effective as a dopamine-related MAO-B inhibitor for mood enhancement.
Use Methylene Blue in SSRI Tapering
- Use methylene blue carefully under medical supervision when tapering off SSRIs to reduce withdrawal symptoms.
- Consider serotonergic support as potentially more effective than only mitochondrial supplementation in this context.
Serotonin's Positive Role
- Methylene blue's benefits likely stem from its serotonergic MAO-A inhibition, which can improve mood and cognitive focus.
- Serotonin is not inherently bad; it can buffer stress and enhance nootropic effects for certain individuals.