
The Gut Health Podcast Gravity Resilience: The Gut-Brain-Diet Connection with Brennan Spiegel, MD
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Oct 1, 2025 Dr. Brennan Spiegel, Director of Health Services Research at Cedars-Sinai, delves into the fascinating concept of gravity resilience and its impact on health. He discusses how our digestive health and mental well-being are intertwined with gravitational forces. Conditions like IBS may connect to joint hypermobility, while the gut produces most of our serotonin. Spiegel also shares practical strategies like the STACK TEN diet, which emphasizes tryptophan-rich foods, and hypopressive exercises to bolster our body's “suspension system.” His insights reveal how gravity affects our emotions and overall health!
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Gravity Resilience Shapes Health
- Gravity resilience is how well your body manages Earth's gravitational force across organs, muscles, and the nervous system.
- Better gravity management improves physical and mental health and reduces chronic conditions tied to gravity intolerance.
Hypermobility Mimicked IBS
- Dr. Brennan Spiegel describes a young woman with hypermobility whose intestines collapsed into her pelvis, mimicking IBS symptoms.
- X-rays showed bowel collapse and treating gravity intolerance with hypopressive exercises, swimming, and tilt-table therapy improved her symptoms.
Space Shows Gravity's Role
- Astronauts in microgravity show gut, immune, and circulatory changes, illustrating the importance of an Earth gravity baseline.
- Both too little and altered relationships to gravity disrupt microbiome, serotonin, and bodily systems.

