Bloody Minded Episode 25 - Alphabet Soup | Overview of Myeloma Treatments
Nov 26, 2024
Dive into the fascinating world of myeloma treatment! Discover the array of drug regimens, from proteasome inhibitors to immunomodulators. Learn about the pivotal role of corticosteroids and the innovative use of monoclonal antibodies. Unpack the complexities faced by older patients and the importance of personalized treatment plans. Explore cutting-edge therapies, including CAR T-cell treatments and their potential to revolutionize patient outcomes. This enlightening journey will give you a new appreciation for the intricacies of managing myeloma.
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Myeloma Treatment Dynamics
- Myeloma treatment involves initial therapy, remission, maintenance, and management of relapse over time.
- Disease progression results from drug-resistant subclones replacing sensitive ones, similar to antibiotic resistance.
Customized Treatment Planning
- Tailor myeloma treatment to patient's age, frailty, comorbidities, and social situation.
- Consider venous access and infection risks before choosing therapy components.
Steroids Are Treatment Backbone
- Use high doses of corticosteroids like dexamethasone as key myeloma therapy components.
- Monitor and manage side effects such as hyperglycemia, hypertension, mood disturbances, and osteoporosis.