The Metabolic Classroom with Dr. Ben Bikman The Link Between Metabolism and Alzheimer’s
Mar 15, 2021
Discover how the brain's energy use ties directly to Alzheimer's risk. The importance of nutrition in maintaining mental health is highlighted, with a focus on the effects of glucose and ketone metabolism. Intriguing research suggests dietary changes could influence cognitive function. The discussions delve into the implications of high insulin levels and the necessity of lowering it through a low-carb diet. Finally, personal stories emphasize the community's role in supporting those impacted by Alzheimer's.
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Plaque Focus May Miss The Root Cause
- Alzheimer's brains show classic plaques and tangles but targeting them hasn't improved outcomes.
- This suggests we should examine other causes beyond anatomical disruptions.
Glucose Deficit, Ketones Preserved
- PET scans showed reduced glucose uptake in mild cognitive impairment and Alzheimer's.
- Ketone uptake remained normal, implying an energy-specific deficit for glucose.
Gene Data Mirrors PET Findings
- Post-mortem gene analysis found reduced expression of genes for glucose uptake in Alzheimer's brains.
- Genes for ketone uptake and metabolism were unchanged.