The Curious Clinicians cover image

The Curious Clinicians

43 - In Vivo Veritas

Feb 16, 2022
The hosts delve into the complexities of testing for anti-phospholipid antibody syndrome during active inflammation, exploring the use of snake venom in hematological testing and factors leading to false elevations. They discuss the link between anti-phospholipid antibody syndrome and inflammation in ICU patients, highlighting the importance of timing in lab testing for accurate diagnosis.
25:12

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Quick takeaways

  • Active inflammation can cause false positives in anti-phospholipid antibody testing, complicating diagnoses.
  • Inflammation and acute illness can interfere with test accuracy for anti-phospholipid antibodies, posing diagnostic challenges.

Deep dives

The Impact of Active Inflammation on Anti-Phospholipid Antibody Testing

Testing for anti-phospholipid antibody syndrome can yield false positives during active inflammation, leading to potential misdiagnoses and unnecessary treatments. The presence of active inflammation can interfere with the accuracy of the test results, causing confusion in diagnosing the syndrome. Understanding the timing of testing and the impact of inflammation is crucial in avoiding misleading outcomes and unnecessary treatments.

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