Link Between Anti-Phospholipid Antibody Syndrome and Inflammation in ICU Patients

The chapter explores a study revealing false positive results for anti-phospholipid antibodies in critically ill patients due to acute inflammation, despite not actually having the syndrome. Factors like CRP levels and sepsis influenced the likelihood of positive test results, challenging the accuracy of lab tests during acute illness. The discussion also includes insights on CRP interference in lupus anticoagulant testing and the importance of repeat testing after the acute phase for accurate diagnosis.