LONGEVITY with Nathalie Niddam #337: This Tiny Molecule Can Tackle Inflammation & Immune Health - Diving into KPV with Nathalie Niddam
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May 23, 2025 Dive into the world of KPV, a remarkable peptide with powerful anti-inflammatory and healing properties. Discover its origins and how it works to combat inflammation, especially in conditions like inflammatory bowel disease. Learn about its potential benefits for gut, skin, and immune health, as well as neuroprotective capabilities. The episode also covers various administration methods and emphasizes the importance of safety protocols while introducing a useful app for tracking peptide treatments.
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KPV Basics and Origins
- KPV is a tiny tripeptide derived from melanotan without tanning effects.
- It primarily acts as a powerful anti-inflammatory and healing agent in the body.
KPV's Anti-Inflammatory Mechanism
- KPV reduces inflammation by blocking NF-kappa B and MAPK pathways inside cells.
- This dual action decreases key inflammatory molecules without affecting skin pigmentation.
KPV Benefits for Gut and Immunity
- KPV shows promise for gut health by reducing inflammation up to 80% in colitis mouse models.
- It also has antimicrobial properties against bacteria like Staphylococcus aureus and fungi like Candida albicans.