JAMA Clinical Reviews
Management of Cirrhosis in 2023
May 9, 2023
Prevalence and causes of cirrhosis in the US, declining prevalence of hepatitis C. Usefulness of history and additional tests in diagnosing cirrhosis. Strategies to improve survival and quality of life for patients with compensated cirrhosis. Management of common symptoms and complications in cirrhosis.
15:06
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Quick takeaways
- Non-alcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are common causes of cirrhosis in the US.
- Regular screening for liver cancer using ultrasound and alpha-fetoprotein is recommended for early detection.
Deep dives
Main Causes and Prevalence of Cirrhosis
Cirrhosis, affecting over 2 million Americans, is commonly caused by non-alcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD). Although hepatitis C used to be a leading cause, increased screening and effective treatment have reduced its prevalence.
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