The Fellow on Call: The Heme/Onc Podcast
New Fellow Bootcamp Series: When Anticoagulation Fails (pt. 1)
Jul 2, 2024
Discover the intriguing world of anticoagulation as the hosts dive into the challenges of medication failures. They explore case studies illustrating why some patients still encounter blood clots, even while on treatment. Learn about the significance of monitoring drug levels and the impact of patient adherence on therapy success. The conversation also touches on when to pivot to traditional anticoagulants like warfarin, bringing a blend of clinical insights and personal anecdotes to keep the discussions engaging and informative!
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Quick takeaways
- Verifying the presence of anticoagulant medications through tests like anti-10A levels is crucial for addressing treatment failures.
- Patient adherence to anticoagulant regimens is vital, as lapses can lead to serious complications, necessitating thorough medication habit assessments.
Deep dives
Understanding Anticoagulation Failure
Anticoagulation failure is a common issue in internal medicine and hematology, where patients on blood thinners still develop clots. The first step in addressing this failure is to verify if the anticoagulant medication is present in the patient's bloodstream. This can be accomplished through an anti-10A level test, which assesses the presence of drugs like rivaroxaban and apixaban, indicating if they're functioning properly. If undetectable levels are found, it can point to adherence problems or issues with absorption rather than a failure of the medication itself.
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