In Search of Insight Cognance - Bacopa Reimagined | The Quest For Ebelin Lactone And A Natural Microdose Alternative
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Dec 6, 2022 AI Snips
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Erika's Bacopa Experience
- Erika initially enjoyed Bacopa for its calming effects.
- However, prolonged use led to lethargy and decreased motivation, causing her to discontinue regular use.
Bacopa Bioavailability
- Bacopa's Bacosides contain large sugar groups, hindering their bioavailability.
- These groups undergo a two-stage hydrolysis in the stomach, converting to bioactive forms like jujobogenin and pseudojujobogenin, which can then convert to ebelin lactone.
Ebelin Lactone's Receptor Targets
- Ebelin lactone interacts with the 5-HT2A receptor and the muscarinic M1 acetylcholine receptor.
- This is unique as few natural, legal compounds affect the 5-HT2A receptor, primarily targeted by psychedelics.