#276 ‒ Special episode: Peter answers questions on longevity, supplements, protein, fasting, apoB, statins, and more
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Oct 23, 2023
Delve into the fascinating prospects of living to 120 and the optimistic theories around longevity. Discover Peter's personalized supplement regimen and the complexities of cholesterol management. The discussion emphasizes the importance of individualized nutrition, especially regarding protein intake and maintaining muscle mass. Explore health-tracking wearables and their impact on metabolic health. Together, these insights challenge conventional wisdom and inspire listeners to rethink their approach to health and longevity.
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insights INSIGHT
Focus on Healthspan, Not Extreme Longevity
Peter Attia doesn't believe current methods allow for dramatically extended lifespans (120+).
He emphasizes focusing on healthspan and delaying age-related decline, not chasing extreme longevity.
volunteer_activism ADVICE
Prioritize Prevention as a Hedge
Prioritize disease prevention and health optimization, even if extreme lifespan extension is unlikely.
Treat this as a hedge against the low odds of a near-term aging breakthrough.
insights INSIGHT
Compressing Morbidity is Key
While Attia believes adding a decade or two to lifespan is possible, he doesn't foresee adding 30-50 years.
He highlights the importance of compressing morbidity and maintaining physical and cognitive function in later life.
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In this special episode of The Drive, Peter discusses a variety of topics, breaking away from the typical deep-dive format to explore a wide range of common questions submitted by listeners. Peter tackles subjects like the viability of living to 120 and beyond, addressing some of the optimistic theories regarding achievement of this remarkable feat. Peter then shares his drug and supplement regimen while emphasizing how individualized these protocols need to be. The conversation also touches on lowering apoB, the long-term use of statins, the myth of good vs. bad cholesterol, the complexities of nutrition research, the quest for the ideal diet, and Peter's strategies for hitting daily protein goals. Peter finishes with a discussion about his favorite health-tracking wearables, the role of CGM in non-diabetics, and more.
We discuss:
Overview of topics and previous episodes of a similar format [2:45];
The viability of living to 120 and beyond: some optimistic theories [4:45];
The potential of mTOR inhibition as a mid-life intervention, and longevity potential for the next generation [13:30];
A framework for thinking about geroprotective drugs and supplements in the context of a lack of aging biomarkers [17:00];
Supplements Peter takes and how his regimen has changed in the last year [26:15];
Pharmacologic strategies to lower ASCVD risk, the limitations of statins, nutritional interventions, and more [36:15];
Misnomers about cholesterol [48:00];
Why nutritional research is so challenging, some general principles of nutrition, and why Peter stopped doing prolonged fasts [50:45];
Optimizing protein intake [59:45];
Wearables for sleep and exercise, continuous glucose monitors (CGM), and a continuous blood pressure monitor on the horizon [1:04:45]; and
The Peter Attia Drive