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Senescent cells are cells that have become damaged and cannot be repaired. As we age, the number of senescent cells in our body increases due to various stresses and damage. These cells can cause inflammation and dysfunction in tissues, leading to accelerated aging. Aging is a result of accumulated damage and programmed changes in our cells.
Fasting can support the removal of senescent cells in the body. Intermittent fasting and prolonged fasting can activate autophagy, a process that helps repair and remove damaged cells. Prolonged fasts, lasting two to three days, may have a more significant effect on removing senescent cells. Fasting provides a period of nutrient scarcity, which prompts cells to go through cleanup and repair processes.
Senolytics are compounds that help remove senescent cells from the body. These compounds target and eliminate damaged cells, promoting tissue rejuvenation. Some senolytics work by altering nutrient-sensing pathways, signaling cells to undergo programmed cell death or be cleared by the immune system. Senolytics can have positive effects on health and aging, helping to maintain vitality and reduce the burden of senescent cells.
The blood type diet, popularized by Peter D'Adamo, suggests that individuals should eat according to their blood type for optimal health. While the scientific evidence supporting this diet is limited, anecdotal reports suggest that following the blood type diet can lead to improvements in various health conditions, potentially impacting aging. The diet focuses on tailoring food choices based on blood type, with different blood types benefiting from specific dietary recommendations.
Senescent cells, which can impact every tissue in the body, are a relatively new area of research that is closely linked to aging. Studies have shown that certain compounds, such as the plant-based compound quercetin, can act as senolytics by selectively eliminating senescent cells. These compounds have been found to have positive effects on various tissues, including the brain, joints, muscle, fat tissue, liver, and heart. Senescent cells increase in number with age, and their removal is seen as a potential way to slow down the aging process.
Studies have shown that exercise and a healthy diet play key roles in slowing down or preventing the accumulation of senescent cells. These lifestyle practices are categorized as xenomorphic, meaning they help either slow down or prevent the formation of new senescent cells. However, once a cell becomes senescent, there is limited scientific evidence on reversing the process through exercise and diet alone. Therefore, a combination of different interventions, including exercise, diet, and specific senolytic compounds, may be necessary to address senescence effectively.
Quality Senolytic is a supplement that combines various senolytic compounds to target senescent cells. The main ingredients include ficetin, a yellow polyphenol that has shown robust senolytic properties, and piper longumine, a compound derived from long pepper with unique senolytic effects. Other ingredients, such as quercetin and optimized curcumin, have been shown to have senolytic effects in specific tissues. Quality Senolytic also includes synactive, a combination of noto ginseng and sweet rose extract, which has been studied for its effects on senescent cells in muscle tissue. These ingredients aim to promote the removal of senescent cells and support healthy aging.
Senescent cells can affect various parts of the body, including the brain. Using a compound called quiescentlytic, which targets senescent cells, can help support brain health and improve cognitive function. Studies have shown that the compound can have a significant impact on brain health, with a 68% increase in the improvement of joint function compared to a placebo group.
Eye strain caused by excessive screen time is a common issue. Staring at screens up close for prolonged periods can lead to dry eyes, discomfort, and other symptoms. Taking breaks from screens, going outside for sunlight in the morning, and keeping the screen at a distance can help reduce eye strain. Neurohacker Collective has developed a vision formula that addresses both the back and front of the eye, as well as the stressed-out muscles, improving overall eye health and reducing eye strain.
Dr. Gregory Kelly is the mastermind behind product development at Neurohacker Collective (neurohacker.com/lukestorey use code LUKESTOREY for 15% off), where his innovative work is revolutionizing how we approach our health and well-being.
An accomplished naturopathic physician (ND) and the author of Shape Shift and over 30 journal articles indexed on PubMed, Dr. Kelly's expertise in nootropics, anti-aging, regenerative medicine, weight management, sleep, and the chronobiology of performance and health is unparalleled.
In today's episode, we dive deep with Dr. Kelly into the intricacies of aging, muscle change over time, and the fascinating world of senescence. We explore how intermittent fasting influences autophagy, debunk common myths about diet and cell turnover, and get an insider's look at the cutting-edge Qualia Senolytic Supplement.
A champion of the senses, no doubt, Dr. Kelly also shares his insights on the future of oral rehydration therapy, the vision formula, and disrupting behavior patterns for better vision. We also take a look at the latest Neurohacker supplements, discussing which products Dr. Kelly personally uses for stress relief, focus, sleep, and more.
Stick around as we unravel the secrets behind effective stress relief products that don't compromise productivity and delve into the exciting results of the Qualia Senolytic Placebo-Controlled Clinical Study. Buckle up for a mind-expanding ride as we connect the dots between cutting-edge science and practical, everyday wellness.
DISCLAIMER: This podcast is presented for educational and exploratory purposes only. Published content is not intended to be used for diagnosing or treating any illness. Those responsible for this show disclaim responsibility for any possible adverse effects from the use of information presented by Luke or his guests. Please consult with your healthcare provider before using any products referenced. This podcast may contain paid endorsements for products or services.
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MORE ABOUT THIS EPISODE:
(00:00:11) How Our Nervous System Responds to the Signal to Noise Ratio
(00:03:17) Greg’s Journey to Naturopathic School & Career Evolution
(00:16:12) The Theories of Aging
(00:28:12) Efficacy of Animal Studies & How Our Muscles Change As We Age
(00:35:30) Understanding Senescence: The Key Part of How We Age
(00:42:56) How To Dump Excess Senescent Cells
(00:53:16) Eating for Your Blood Type
(00:56:35) Brain Aging & Senescent Cells
(01:03:39) Inside the Qualia Senolytic Supplement
(01:27:23) Exploring the Future of Oral Rehydration Therapy
(01:31:22) Examining the Vision Formula & Preserving Eye Health
(01:43:57) New & Noteworthy Neurohacker Supplements
(01:55:05) Qualia Senolytic Placebo-Controlled Clinical Study Results
Resources:
The Life Stylist is produced by Crate Media.
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