

Episode 229 -- May 2025 -- Part 1 AFP: American Family Physician
May 16, 2025
Discover the complexities of trigeminal neuralgia and the effectiveness of treatments like carbamazepine. Delve into the emerging role of sodium-glucose cotransporter-2 inhibitors in managing chronic kidney disease and type 2 diabetes. Unpack the nuances of female sexual dysfunction, its diagnostic criteria, and therapeutic options. Explore the alarming health risks posed by PFAS exposure, especially for firefighters, and review the challenges surrounding methotrexate in treating juvenile idiopathic arthritis.
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Trigeminal Neuralgia Characteristics
- Trigeminal neuralgia typically causes intense, brief, shock-like unilateral facial pain often triggered by stimuli like chewing or talking.
- Diagnosis relies mainly on clinical features, but MRI is recommended to exclude other causes like tumors or multiple sclerosis.
Trigeminal Neuralgia Treatment Advice
- Use carbamazepine as the first-line drug for trigeminal neuralgia to reduce pain intensity and frequency.
- Consider surgery for patients with refractory symptoms and transcutaneous electrical nerve stimulation as a possible adjunct.
Early Medication Abortion Safety
- Early medication abortion before intrauterine pregnancy confirmation is safe and effective with high completion rates.
- Early treatment leads to shorter bleeding duration and higher satisfaction, despite a slightly higher ongoing pregnancy rate.