GLP-1s & Menopause: The Science Behind the Hype - #124

In this episode of The Health Trip Podcast, we dive into one of the most talked-about—and misunderstood—topics in women’s health: GLP-1 medications and midlife metabolism.

If you’ve noticed changes around your waistline during perimenopause or menopause, you’re not imagining it. By age 50, nearly half of women develop some degree of insulin resistance, increasing risk for diabetes, heart disease, Alzheimer’s, and more.

My guest, Dr. Dana Russo, board-certified gynecologist and founder of Essenza Health, unpacks the science behind GLP-1s (Ozempic, Wegovy, Zepbound). Together, we explore:

How menopause affects metabolism and insulin sensitivity

Why GLP-1s are about more than weight loss—they target inflammation, insulin resistance, and longevity

The role of menopause hormone therapy and lifestyle in supporting metabolic health

The differences between FDA-approved vs. compounded GLP-1 medications

If you’ve wondered whether these drugs can be part of a safe, long-term strategy for women in midlife, this conversation cuts through the noise and gets to the science.

Medical Disclaimer:

By listening to this podcast, you agree not to use this podcast as medical advice or to make any lifestyle changes to treat any medical condition in yourself or others. Consult your own physician for any medical issues that you may be having. This entire disclaimer also applies to any of my guests on my podcast.

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