This Podcast Will Kill You

Ep 183 SSRIs Part 2: Action

11 snips
Jul 29, 2025
Dive deep into the fascinating world of SSRIs and discover how they interact with serotonin. Hear personal journeys of individuals reclaiming their lives from anxiety and OCD through these medications. Explore the historical context and the complicated discourse surrounding SSRIs and their effectiveness. Unpack the nuances of serotonin syndrome and the importance of personalized treatment approaches. Plus, enjoy some humorous metaphors making neuroscience a little more engaging!
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ANECDOTE

Haley's Transformative SSRI Journey

  • Haley shares her personal experiences with Zoloft managing anxiety and OCD symptoms.
  • She highlights how SSRIs helped her function and pursue goals like applying to medical school.
ANECDOTE

Sarah's OCD and SSRI Success

  • Sarah recounts her struggles with OCD and how SSRIs enabled her to manage obsessions.
  • This support allowed her to finish her master's and pursue a PhD.
INSIGHT

SSRI Mechanism and Brain Compensation

  • SSRIs block serotonin reuptake transporters, raising serotonin levels in the synapse.
  • But therapeutic effects lag because brain receptors adjust to maintain balance, complicating the response.
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