Healthy Living Healthy Living - September 8th
Sep 8, 2024
The hosts dive into the risks of long-term PPI use for reflux and highlight the search for alternatives. An innovative malaria treatment using cholesterol is discussed, alongside exciting developments in Alzheimer's research, including a potential vaccine. Listeners learn about groundbreaking prostate cancer trials and advancements in inflammation monitoring tech. Plus, new migraine relief solutions and the impact of gut health on diabetes are explored, making for a captivating blend of health insights and breakthroughs.
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Step Down Chronic PPI Use
- If you rely on daily PPIs, discuss stepping down with your GP and consider H2 blockers first.
- Use a PPI as an occasional rescue on bad reflux days rather than daily to reduce long-term risks.
Potential Long-Term Harms Of PPIs
- Long-term PPIs associate with several signals of harm including gastric cancer, kidney injury, vascular endothelial dysfunction and increased dementia risk.
- These are relative-risk signals that require balancing against the severity of reflux symptoms before changing therapy.
Manage Reflux By Balancing Risks
- Treat reflux by balancing symptom burden against drug risks and aim to minimise daily PPI exposure where possible.
- Try H2 blockers daily and reserve PPIs for breakthrough symptoms under GP supervision.