

205. Brooke Siem on Medicating Unhappiness and SSRI Withdrawal
Brooke Siem is the author of the 2022 memoir, May Cause Side Effects, about the decade and a half she spent on anti-depressants (prescribed after her father died when she was 15) and what happened when she ditched them. Sarah is currently on anti-depressants, though she wonders whether she needs them. Nancy is not on SSRIs, though she was part of a gentle brigade who nudged Sarah to increase her dosage last year. This is a complicated knot! The ladies talk about over-medication, how cultural taboos migrate, and the problem with treating sadness, anger, frustration — very human emotions — with a pill.
Also discussed:
* Nancy suddenly cares about the Navy; Sarah questions this
* That time Brooke wore a foxy denim jumper
* “Chemical imbalance” is a hoodwink
* The “Come Out of the Dark Campaign” meant to eradicate depression stigma leads to an explosion of SSRI prescriptions
* SSRIs and orgasm
* The opiate epidemic tracks with the anti-depressant era
* “Chemical castration” didn’t start with puberty blockers …
* 70s-80s Ritalin vogue
* Related: Does Ritalin suppress male growth?
* Hold up: a link between transitioning genders and SSRIs?
* Drinking and depression, a tangled saga
* “Headaches are caused by an Advil deficiency”
* Beware Wellbutrin
* Gothic SSRI withdrawal
* “I never boned a cabbie … that I’m aware of.”
* That time Sarah went hypomanic …
* 1 in 4 American women are on anti-depressants
* The hormones and menopause of it all
* “Fuck you, person at Whole Foods!”
* Big Pharma / Big Food = same playbook, different expression
* “Do you bake with yeast?”
* WTF with Pol Pot?
Plus, boozy cupcakes, a coyote sighting, was Tom Cruise right about pharmaceuticals — and much more!
This one’s a banger! Listen to the whole shebang when you become a paid subscriber.