Metabolic Matters Beyond Genetics: How Mitochondria, Folate & the Microbiome Shape Autism w/ Dr. Richard Frye
Episode Summary: In this deeply insightful episode, Dr. Nasha Winters is joined by renowned pediatric neurologist and researcher Dr. Richard Frye. With decades of experience and hundreds of peer-reviewed publications, Dr. Frye shares his groundbreaking work in autism spectrum disorder, particularly its links to mitochondrial dysfunction, neuroinflammation, and metabolic abnormalities.
You'll learn how Dr. Frye's clinical and lab research is reshaping the narrative around autism—from a strictly genetic and behavioral model to a more hopeful, treatable biomedical framework.
They dive into:
The mitochondrial abnormalities often present in children with autism
The role of oxidative stress, folate transport issues, and methylation
Why nutrition and prenatal health matter more than ever
How treatments like leucovorin, B12, CoQ10, and lifestyle changes can support better outcomes
The promising intersection of microbiome therapy, metabolic testing, and real-world clinical care
This is a must-listen for clinicians, caregivers, and anyone passionate about innovative approaches to autism care.
Guest Bio:Dr Frye is a Harvard trained Child Neurologist who received both an MD and PhD from Georgetown University. Dr. Frye is a national leader in autism spectrum disorder (ASD) research, particularly metabolic disorders, and has authored over 300 publications. He has developed the Metabolic Learning Resource which has recently released The Folate Fix. He is President and Chief Scientific Officer of the Autism Discovery and Treatment Foundation, Chief Medical Officer of the Neurological Health Foundation, Director of Research and Neurologist at the Rossignol Medical Center.
🔗 Connect with Dr. Richard Frye:
Wesbite: https://drfryemdphd.com/
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