PRS Journal Club

VYC-20L to Correct Temple Hollowing” with Lara Devgan, MD, MPH - Jul. 2025 Journal Club

Jul 2, 2025
Join renowned aesthetic plastic surgeon Lara Devgan as she delves into the latest findings on using VYC-20L hyaluronic acid filler for correcting temple hollowing. With an impressive background from Yale and Johns Hopkins, Dr. Devgan shares her insights on the safety and effectiveness of this treatment based on a multicenter randomized controlled trial. Discover the nuances of facial aging, volumization techniques, and the inspiring integration of surgical and injectable methods for personalized patient care.
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INSIGHT

Voluma Shows High Long-Term Response

  • The randomized multicenter trial showed 80.4% responder rate at month 3 and 73% at month 13.
  • Blinded investigator assessments and FACE-Q scores confirmed durable improvement.
INSIGHT

No Serious Vascular Events Reported

  • Treatment-associated adverse events were mostly minor, like jaw pain and headache, occurring in 18% of participants.
  • Authors reported no vascular occlusions or vision changes and all events resolved without intervention.
INSIGHT

Impressive RCT With Tough Control Arm

  • The multicenter randomized design and blinded assessments strengthened evidence for Voluma.
  • Amanda Sergesketter praised recruiting many patients willing to stay untreated in the control arm.
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