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Diabetes Core Update
Diabetes Core Update Jan 2024
Dec 27, 2023
This podcast covers a range of interesting topics including the effects of treatment on major adverse cardiovascular events in individuals with diabetes, a study on intensive weight management for type 2 diabetes remission, the efficacy and safety of a total dietary replacement program for weight loss, and the importance of understanding and addressing Cardiovascular Kidney Metabolic Health (CKM).
35:11
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Quick takeaways
- The use of semaglutide, a GOP-1 receptor agonist, in individuals with obesity or overweight without type 2 diabetes resulted in a 20% reduction in cardiovascular events compared to placebo.
- The total cost of diagnosed diabetes in the United States in 2022 was estimated to be $412 billion, emphasizing the need for prevention and management strategies.
Deep dives
Sumaglotide and Cardiovascular Outcomes in Obesity Without Diabetes
The podcast discusses a landmark trial that tested the effect of a GOP-1 receptor agonist, maglotide, in individuals living with obesity or overweight without type 2 diabetes. The trial involved 17,000 participants who were randomized to receive either semaglotide or placebo. After three years of observation, the semaglotide group showed a 20% reduction in the composite endpoint of death from cardiovascular causes, non-fatal MI, and non-fatal stroke compared to the placebo group.
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Listen to the best highlights from the podcasts you love and dive into the full episode