
The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch 20VC: The 3 Forms Of Edge A Founder Can Have, Lessons From Being on A Board With Bill Gates & Why There Are A Lot Of Tourist VCs Who Are Going To Lose A Lot Of Money, with Josh Wolfe, Co-Founder @ Lux Capital
May 10, 2017
Josh Wolfe, a Co-Founder and Managing Partner at Lux Capital, dives into the world of venture capital, discussing his unique journey from science labs to investing. He shares his insights on thematic investing and warns of 'tourist VCs' poised to lose big. Wolfe explains how he identifies the tipping point where heavy science becomes commercialized, emphasizing the need for a robust methodology. He also addresses concerns regarding R&D investment trends and the implications of shorter liquidity cycles in today's market.
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Josh Wolfe's Career Journey
- Josh Wolfe transitioned from science to finance inspired by his mentor trading futures while running an immunopathology lab.
- He found venture capital a perfect hybrid of science and finance, thriving on risk and uncertainty.
Frontiers of Innovation
- Technological frontiers are iterative but combinatorial advances feel like new eras.
- Renaissance-style interdisciplinary thinkers drive breakthrough innovations by connecting specialized fields.
Specialization and Passion in VC
- Vertical specialization in VC has benefits but can cause inflexibility if market interest shifts.
- Passionate deep-focus on frontier science investing differentiates firms like Lux Capital amid many tourist VCs.




