In this intriguing discussion, Dr. Andrew Steele, a scientist and the author of 'Ageless,' shares his expertise on the biology of aging. He explores groundbreaking research that could help slow or even reverse aging. With insights on lifestyle choices, he highlights how these can enhance both lifespan and healthspan. The conversation also delves into innovative treatments like senolytic drugs and cellular reprogramming, while raising ethical questions surrounding longevity and overall health, including the surprising impact of oral hygiene.
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insights INSIGHT
Internal and External Aging
External cosmetic signs of aging are only one aspect.
The same processes causing wrinkles also increase the risk of diseases like cancer and dementia.
insights INSIGHT
Biological vs. Chronological Age
Biological age measures age based on cellular and molecular changes, not just chronological age.
Epigenetic clocks use DNA markers to assess biological age and predict disease risk.
insights INSIGHT
Hallmarks of Aging
Aging isn't a single process but a combination of interconnected hallmarks.
These include DNA damage, senescent cells, and a weakening immune system.
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The New Science of Getting Older Without Getting Old
Andrew Steele
In 'Ageless,' Andrew Steele delves into the laboratories where scientists are studying every bodily system that declines with age, including DNA, mitochondria, stem cells, and the immune system. He argues that aging is not an inevitable biological process but rather a disease that can be prevented and potentially reversed. The book covers the history of aging research, current advancements, and future prospects for therapies such as senolytics, gene therapy, and stem cell treatments. Steele presents a hopeful and optimistic view of the potential for significant life extension and improved healthspan through these scientific breakthroughs[3][4][6].
For centuries, people have pursued the dream of eternal youth. It might seem like the stuff of myth or science fiction, but researchers have been making fascinating progress in understanding what happens in our bodies as we age. There’s optimism that we might soon be able to use drugs to slow down or even reverse how we age, extending the number of years we live healthy, productive lives. What’s more, some of us might be taking these drugs already.
On today’s episode, Lucy Hockings speaks to Dr Andrew Steele, author of ‘Ageless: The new science of getting older without getting old’ to find out whether we might drink from the fountain of youth in our lifetime.
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