
Long Covid Podcast 173 - Diana Driscoll - Healing PoTS and Dysautonomia: From Patient to Pioneer
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Apr 30, 2025 Diana Driscoll, a clinician and researcher, transformed her ten-year battle with POTS and dysautonomia into groundbreaking medical advances. In this conversation, she explains the connection between inflammation and cardiovascular issues in POTS, revealing the 'Driscoll Theory' linking high intracranial pressure to symptoms. Diana discusses her patented supplement, Parasym Plus, designed to address neurotransmitter deficiencies and outlines the unique challenges faced by female patients. Her insights emphasize proactive health management and the importance of understanding individual inflammatory triggers.
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Patient Turned Researcher
- Diana Driscoll became bedridden with post-viral dysautonomia and spent over ten years disabled while seeking answers.
- Her children's similar illnesses pushed her to research, patent treatments, and found new clinical approaches.
POTS Is A Symptom, Not A Disease
- POTS is a presentation (fast heart rate on standing), not a single disease, and often misleads clinicians toward cardiac causes.
- Diana says the common thread across POTS, dysautonomia, and long COVID is inflammation affecting the cardiovascular system.
Hormones Amplify Vascular Inflammation
- Female hormonal surges (estrogen) amplify vascular inflammation and worsen POTS symptoms, explaining higher female prevalence.
- Males may have milder courses partly due to fewer hormonally driven inflammatory swings.

