5 Medications That Increase Gut Inflammation

Jun 13, 2025

Discover how common medications like NSAIDs can wreak havoc on your gut health, contributing to problems like leaky gut and inflammation. Learn about the unexpected harms of unnecessary antibiotics and their role in bacterial resistance. Dive into the issues with acid-blocking medications, which can hinder nutrient absorption, and hear about the potential long-term risks associated with birth control pills and steroids. This eye-opening discussion emphasizes the importance of understanding what you're putting in your body.

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ANECDOTE

Overuse of Ibuprofen in Youth

Dr. David Jockers took up to nine ibuprofen a day as a teenager for arm soreness.
He believes that overuse contributed to developing irritable bowel syndrome.

INSIGHT

Gut Inflammation Causes Systemic Aging

Chronic inflammation starts with gut lining breakdown causing toxins to enter the bloodstream.
This triggers systemic inflammation that accelerates aging from the inside out.

ADVICE

Medications Treat Symptoms Only

Medications usually only address symptoms, not root causes, akin to pulling trash from a river without stopping the source.
Focus on lifestyle changes to address underlying causes of health issues.

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In this episode, Dr. David Jockers reveals how common pain relievers like NSAIDs can damage your gut, leading to leaky gut and inflammation. He shares the science behind how these meds worsen long-term gut health.

Antibiotics, often prescribed unnecessarily, disrupt the gut microbiome and cause more harm than good, creating long-term issues like bacterial resistance.

Dr. Jockers also explains how acid-blocking medications prevent nutrient absorption, particularly B12 and magnesium, and why they’re more damaging than helpful.

In This Episode:

00:00 Personal Story: The Dangers of Overusing Ibuprofen

00:41 Introduction to the Podcast and Sponsor Message

03:02 Understanding Gut Inflammation and Medications

07:43 The Problem with NSAIDs

09:38 The Risks of Antibiotics

13:40 The Dangers of Acid Blocking Medications

16:56 Issues with Birth Control Pills

17:37 Steroids: Short-Term Relief, Long-Term Harm

18:38 Conclusion and Final Thoughts

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“I ended up taking eight or nine ibuprofen a day to help relieve the soreness in my arm. And I really believe that was one of the triggers for me developing irritable bowel syndrome”

~ Dr. Jockers

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Resources:

Visit https://shopc60.com/jockers – Use code “JOCKERS” to get 15% off!
Visit biOptimizers.com/Jockers

Connect with Dr. Jockers:

Instagram – https://www.instagram.com/drjockers/
Facebook – https://www.facebook.com/DrDavidJockers
YouTube – https://www.youtube.com/user/djockers
Website – https://drjockers.com/

If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/