The Clinical Problem Solvers

Episode – 399 – RLR – Ascites

Jun 2, 2025
The hosts share amusing pet anecdotes, setting a light conversational tone. They dive deep into ascites and chylous effusion, discussing fluid analysis methods. A case study features a 64-year-old man with bilateral hydronephrosis, exploring complex differential diagnoses. The critical evaluation of a chest x-ray reveals intriguing connections to heart and lymphatic issues. They also tackle a challenging case with idiopathic ureteral stenosis, highlighting the importance of teamwork and open dialogue among medical professionals.
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ANECDOTE

Initial Fluid Collection Anecdote

  • Robbie first saw two colleagues collecting a large volume of fluid from the peritoneal space in the emergency room.
  • The fluid was nearly bloody and milky, sparking an initial suspicion of chylous ascites.
INSIGHT

Milky Fluid Indicates Chylous Ascites

  • Milky fluid that separates into layers suggests chylous ascites with high triglycerides.
  • This fluid is often lymphocyte predominant and indicates lymphatic disruption.
INSIGHT

High SAG in Chylous Ascites Explained

  • A serum ascites albumin gradient (SAG) above 1.1 suggests portal hypertension; below indicates exudative causes.
  • This case had high SAG despite milky fluid, implying precise lymphatic leakage without widespread endothelial disruption.
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