Delirium is a serious problem in hospitalized patients, doubling the risk of death and causing cognitive and functional impairment.
Non-pharmacologic strategies, such as orientation, cognitive stimulation, and sleep enhancement, are effective in preventing delirium.
Deep dives
Understanding Delirium and Its Clinical Features
Delirium is a serious problem in hospitalized patients, doubling the risk of death and causing cognitive and functional impairment. Delirium is common, affecting approximately one in five inpatients, with higher rates in surgery and intensive care units. It is marked by inattention, disorientation, thought disorganization, fluctuating symptoms, disrupted sleep-wake cycles, and emotional changes. Delirium can be categorized into hypoactive, hyperactive, and mixed types, each requiring specific attention. Certain factors, including age, cognitive impairment, medication use, and medical conditions, increase the risk of delirium.
Identifying and Evaluating Delirium
To identify delirium, healthcare providers should review patient charts, assess mental status changes, ask basic questions about the patient's hospital experience, and obtain collateral history. Screening tools like the Confusion Assessment Method (CAM) or the 3D CAM can improve diagnosis. Evaluations should be repeated due to the fluctuating nature of delirium. Physical and neurologic exams, reviewing vital signs, medications, and ruling out underlying medical causes can help determine the cause of delirium.
Prevention, Management, and Treatment of Delirium
Non-pharmacologic strategies are effective in preventing delirium and include orientation, cognitive stimulation, and sleep enhancement. Mobilization, hydration, infection prevention, and proper nutrition also play a crucial role. Treatment involves addressing underlying medical causes. Antipsychotics can be used for acutely agitated patients, but their effectiveness is limited, with potential sedative effects and risks. Alternative treatments include bupropion, alpha-2 agonists, and trazodone. Benzodiazepines are generally avoided and reserved for withdrawal cases. Use medications sparingly while identifying and treating the underlying cause of delirium.
Delirium is widespread among patients in ICUs and surgery units. In this podcast, we will review the workup and management of this common condition and give you tips to help prevent it in high-risk patients
Victoria Hendrick, MD, and Prabhjot Gill, BS, have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.
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