High Performance Longevity #221 Decode 1,700 Biomarkers & Disease Risk 10 Years Early With 1 Drop of Blood (TruHealth Test) | Ryan Smith @ TruDiagnostic
Standard blood tests barely scratch the surface.
Ryan Smith shares how TruDiagnostic’s TruAge & TruHealth tests use over 1,700 biomarkers from just a drop of blood to measure biological age, hormone health, immunity & more. Go beyond standard labs & start bioharmonizing with cutting-edge precision so you can make decisions that actually impact how you feel & age.
Meet our guestRyan Smith studied Biochemistry at Transylvania University before founding Tailor Made Compounding, which became one of the fastest-growing healthcare companies in the U.S. After exiting in 2020, he launched several ventures, including TruDiagnostic, a CLIA-certified lab specializing in methylation-based diagnostics for longevity & preventive health.
TruDiagnostic leads the field with one of the largest private epigenetic databases, over 13,000 patients, & active participation in 30+ clinical research studies. Ryan remains a key figure in advancing functional medicine through innovative health data solutions.
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- Biological age gives a clearer picture of health risk than birthdate by showing how your body is actually aging
- Lifestyle basics like exercise, clean eating, stress reduction & social connection remain top tools for aging well
- Some biological age tests are more reliable thanks to stronger prediction power & actionable results
- Longevity interventions can now be ranked using technology that tracks measurable improvements over time
- Leading tests don’t just score your age but give clear next steps to improve healthspan & lifespan
- DNA methylation data offers biomarker proxies that sometimes outperform traditional blood tests
- Methylation-based tests bring better precision & consistency than standard lab results affected by daily shifts
- Immune system strength plays a major role in aging by influencing inflammation & clearing damaged cells
- Supplement & lifestyle tracking tools now show whether specific changes are actually improving key health markers
- TruAge tests work well for most while biohackers may benefit more from deeper panels like the TruHealth test
3:29 What Biological Age Really Tells You
10:12 Inside TruDiagnostic’s Testing Framework
11:39 Key Lifestyle & Supplement Insights from the Data
15:10 How to Interpret Your Report & Take Action
30:12 Understanding Your Immune & Metabolic Health
45:29 Practical Application & Future of Epigenetic Testing
Links- Watch it on YouTube: https://youtu.be/MykPl4fZ3Sc
- Full episode show notes: outliyr.com/221
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Nick