LONGEVITY with Nathalie Niddam #353: Melatonin 101: Antioxidants, Gut Health, Sleep, Skin Protection, and Cancer Research with Nat Niddam
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Jul 18, 2025 Dive into the fascinating world of melatonin! Discover why this hormone is more than just a sleep aid, with its roles in antioxidant defense and gut health. Explore the effects of light exposure, aging, and synthetic versus natural sources. Learn practical dosing tips, potential interactions, and the latest research on melatonin's anti-cancer properties. Find out how melatonin might enhance your overall health and well-being while navigating its complex benefits.
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Melatonin: Darkness Hormone Insight
- Melatonin is the darkness hormone opposite to vitamin D, the daylight hormone.
- It plays complex roles beyond sleep, including skin and mitochondrial protection.
Gut Produces Most Melatonin
- Melatonin is produced in both the pineal gland and the gut.
- The gut produces 400 times more melatonin, which influences gut motility and antioxidant protection.
Melatonin Declines with Age
- Human melatonin levels decline from the 20s to 50s, dropping notably over 50.
- This decline supports the rationale for melatonin supplementation with age.
