
 The Energy Blueprint Podcast
 The Energy Blueprint Podcast How Do Mitochondria Respond To Health And Disease? | Eric D. Gordon, MD
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 Oct 25, 2025  Dr. Eric D. Gordon, with over 40 years of experience, discusses the history of alternative medicine, major aspects of health missed by functional medicine, the real reason behind chronic fatigue, and the intelligence of the body. They explore the concept of sickness behavior, the need for a systems approach in understanding human biology, and the role of mitochondria in the cell danger response. The power of the mind in healing and finding joy for health and wellbeing is also emphasized. 
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Boxes Of Supplements That Didn't Help
- Dr. Gordon received patients carrying boxes of supplements without improvement.
- That experience led him to question the 'broken mitochondria' model.
Mitochondria Are Immune Sensors
- Mitochondria function as immune sensors, not just powerhouses.
- They respond to danger signals by changing behavior rather than being inherently broken.
Extracellular ATP Signals Danger
- Mitochondria export ATP as an early danger/inflammation signal to neighboring cells.
- Extracellular ATP triggers immune activation before hormones and later inflammatory cascades.
