Neurology® Podcast Effects of Intensive Lifestyle Changes on the Progression of MCI or Early Dementia
Feb 11, 2025
Dean Ornish, founder of the Preventive Medicine Research Institute, shares insights on transformative lifestyle changes for improving cognition in early dementia. He discusses groundbreaking research showing significant cognitive enhancements through non-drug interventions. The importance of social support and cognitive engagement is emphasized, highlighting how meaningful conversations can uplift those affected by dementia. Ornish also explores the success of remote clinical trials during the pandemic and the potential for Medicare to cover these life-changing strategies.
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Lifestyle Interventions Improve Cognition
- Intensive lifestyle interventions can significantly improve cognition and function in patients with MCI or early dementia.
- This offers hope beyond existing drugs that only slow deterioration.
Value of Early Diagnosis
- Early intervention in Alzheimer's is crucial and likely more effective.
- New AI tools enable diagnosis years before symptoms, opening prevention opportunities.
Statistical Evidence of Benefit
- The study showed significant cognitive improvement in lifestyle group vs control across multiple measures.
- 71% of intervention patients improved or stabilized, while none improved in control and 68% worsened.