The Contemplative Science Podcast Rewiring Hope: Computational Models, Psilocybin, and the Science of Optimism w/ Beth Fisher
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Dec 15, 2024 In a fascinating discussion, Beth Fisher, a PhD student at M3CS, unpacks her innovative research on psilocybin's effects on optimism and decision-making. She reveals how psilocybin can modify the brain’s approach to loss aversion and enhance hopeful engagement in rats. Delving into therapeutic potential, Beth discusses the role of environment in psychedelic therapy and how computational models help measure optimism. With insights into gratitude’s impact on perspective, she offers a unique lens on fostering resilience in challenging times.
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Optimism Is Adaptive
- Optimism, overestimating positive outcomes, is adaptive.
- It encourages engagement with the world, leading to better life outcomes.
Psilocybin's Impact on Optimism
- Psilocybin increased optimistic behavior in rats by modifying belief updating.
- Rats learned more from wins and less from losses, amplifying optimism bias.
Mechanism-Focused Research
- Research aims to understand psilocybin's mechanisms to identify suitable patients.
- This approach helps maximize benefits and minimize potential risks.