

Episode 456: Unexpected Findings from Beta-Blockers and Beyond
Sep 9, 2025
Discover surprising findings about beta-blockers and heart attack recovery, revealing women's higher mortality risk. Delve into discussions on health supplements like taurine and spermidine, as well as the controversial effects of artificial sweeteners. Explore new insights on meal timing and ketogenic diets. Dr. Joel Kahn encourages ongoing conversations with healthcare providers about these unexpected medical revelations and how they might affect treatment options.
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Beta-Blockers May Harm Some Women After MI
- A large randomized trial found no overall benefit to beta-blockers after MI when EF >40%.
- Surprisingly, women discharged on beta-blockers had higher mortality while men did not.
Talk To Your Doctor Before Changing Beta-Blockers
- Do not stop your beta-blocker without consulting your physician.
- If you're a woman with recent MI and EF>40%, discuss the new study with your cardiologist.
Clopidogrel Outperformed Aspirin In Big Review
- A large review in The Lancet found clopidogrel outperformed aspirin for many patients and caused less GI bleeding.
- This challenges the long-standing default of low-dose aspirin after coronary disease.