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The Gillett Health Podcast
CAG Repeats | The Gillett Health Podcast #60
Feb 5, 2024
The podcast discusses CAG repeats and their impact on various aspects of health, such as sexual function, reproductive health, prostate health, cardiovascular health, and bone density. They also explore the relationship between CAG repeats and athletic performance, as well as the effects of androgen receptors and testosterone on different conditions. The hosts emphasize the importance of knowledge in therapy outcomes and the relevance of weak and strong androgens in overall wellbeing.
38:59
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Quick takeaways
- CAG repeats can impact sexual function and the response to testosterone replacement therapy (TRT), with shorter repeats correlating to better improvements in sexual function.
- Individuals with longer CAG repeats may be at a higher risk of developing prostate cancer and experiencing more severe coronary artery disease.
Deep dives
Impact of CAG repeats on testosterone sensitivity
The podcast episode explores the impact of CAG repeats on testosterone sensitivity. Individuals with longer CAG repeats tend to have a higher TRT dose, while those with lower CAG repeats may require a lower dose. However, there is no established formula for determining the ideal dose based on CAG repeats. The episode discusses potential implications for sexual function, testosterone replacement therapy, prostate health, bone density, cardiovascular disease, and body composition. It also mentions a study on Russian athletes, which found that Olympic weightlifters had higher CAG repeat numbers. The episode concludes by highlighting the need for further research and the availability of CAG repeat testing.
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