Blog summary of an editorial published in Volume 14 of Oncotarget, entitled, “The role of Kras and canonical Wnt pathways for tumorigenesis of extrahepatic biliary system.”
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The extrahepatic biliary system is a network of tubes and ducts that carry bile from the liver to the small intestine, where it helps digest fats. Biliary tract cancers, including gallbladder cancer and cholangiocarcinoma, are rare but aggressive cancers that arise from this system. Understanding the molecular mechanisms that drive these cancers is crucial for developing effective therapies.
“Despite advances in diagnosis and therapy, 5-year survival rate of biliary cancer is only 5% to 15% [7, 8].”
In a new editorial, researchers Munemasa Nagao, Akihisa Fukuda and Hiroshi Seno from Kyoto University Graduate School of Medicine discuss the latest research on the role of Kras and the canonical Wnt pathway in the development of biliary tract cancers. On January 26, 2023, their paper was published in Oncotarget’s Volume 14, entitled, “The role of Kras and canonical Wnt pathways for tumorigenesis of extrahepatic biliary system.”
Full blog - https://www.oncotarget.org/2023/03/01/the-role-of-kras-and-canonical-wnt-pathways-in-biliary-tract-cancers/
DOI - https://doi.org/10.18632/oncotarget.28349 (PDF Download)
Correspondence to - Akihisa Fukuda - fukuda26@kuhp.kyoto-u.ac.jp
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Keywords - ICPN, BilIN, biliary cancer, Kras, Wnt
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