Episode #452: “We still had a lot of ideals… but we had some illusions, so to speak.”
François Nosten has spent decades on the Thai-Myanmar border, where war, disease, and displacement overlap endlessly. He arrived in the 1980s, a young doctor from Toulouse with Médecins Sans Frontières, drawn by a sense of purpose. What he found was devastation: malaria sweeping through camps, killing faster than bullets. “There were more of the student dying of malaria than from the fighting,” he recalls of the post 1988 movement.
Nosten met British scientist Nicholas White, and their work helped pioneer artemisinin-based treatments, which transformed malaria care worldwide. “If you test and treat systematically, early, quickly, then the people don't die anymore,” he explains. For a moment, it seemed victory was possible: “One year later, malaria was gone from the Thai side.” But the disease returned, mutating and persisting through poverty and conflict.
When Myanmar’s 2021 coup collapsed its health system, millions were displaced. Aid stopped, clinics closed, and outbreaks flared again. “Tuberculosis is still very serious worldwide… more than HIV,” he warns. “If funding is being cut… I think that tuberculosis will explode again.” Nearby, scam compounds now imprison thousands in unsanitary, lawless towns. “They are like towns,” he says, almost as big as Mae Sot itself.”
Nosten still reflects on the conviction and purpose that drove his early ambition as a young doctor. “I did my medical school to be able to travel and to do something that I think was useful,” he says. Now, decades later, he continues that same work, even as the border he serves teeters once again on the edge of collapse.
“If you have a stable country… you can control malaria,” Nosten says. “But here, everything conspires against stability.”


