Impact of Niacin on Cholesterol Levels

Niacin, or vitamin B3, plays a significant role in managing cholesterol levels, particularly in patients with specific cardiovascular risks. A case was shared where a patient with a calcium score of zero but carotid plaque exhibited a substantial decrease in cholesterol levels after being placed on an extended-release niacin regimen. This resulted in a reduction of total cholesterol by approximately 35% and a notable drop in LDL particle numbers and lipoprotein A levels. Such findings reinforce the efficacy of niacin as a viable alternative to statins, especially in cases where standard medications might not be effective or appropriate.