The Carlat Psychiatry Podcast
Uncontrolled Misuse
Oct 23, 2023
Discussing the increasing misuse of medications like bupropion, quatypine, and gabapentinoids, and the need to address this national crisis. Exploring the misuse of prescription medications, addiction as a chronic brain disease, and the criteria for defining addiction. Focusing on the misuse and abuse potential of commonly prescribed medications, including bupropion. Exploring the differences in anticholinergic effects, the abuse potential of certain drugs, and the spectrum of altered mental states.
24:34
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Quick takeaways
- Misuse of uncontrolled medications, such as bupropion, quetiapine, and gabapentinoids, is a rising trend, contributing to increasing drug overdose deaths.
- The definition of addiction has evolved to include behavioral and cognitive components, emphasizing brain circuitry and excessive drug self-administration.
Deep dives
Increase in misuse of uncontrolled medications
Misuse of uncontrolled medications, such as bupropion, quatypine, and gabapentinoids, is a new trend in medication misuse. Patients are taking these medications in excessive amounts, often through non-traditional routes like snorting, and co-administering them with other drugs of abuse. The misuse also includes malingering psychiatric symptoms to obtain prescription medications and the diversion of prescriptions for monetary gain or exchange. This rise in medication misuse contributes to the increasing number of drug overdose deaths, which is a national crisis.
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