Siim Land Podcast #467 I Analyzed Bryan Johnson's Biomarkers and The Results Are...
Aug 23, 2025
The discussion delves into a detailed comparative analysis of health biomarkers between two individuals. It highlights intriguing differences in fitness, body composition, and metabolic health. Listeners will learn about inflammation and immune markers, alongside cardiovascular and kidney health indicators. The conversation also touches on hormone levels and experimental tests for longevity. Plus, a fascinating look at the PhenoAge biological age test adds depth to the exploration of how one can rewind their biological clock.
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Comparison Debunks Universal 'Best Biomarkers' Claim
- Siim compared 65+ biomarkers and found he had better results in 44, Brian in 9, and 12 equal.
- This disproves Bryan Johnson's claim of having the best biomarkers globally regardless of age.
Fix Iron To Raise VO2max
- Improve VO2max by addressing iron and hemoglobin status, since oxygen-carrying capacity limits maximal aerobic fitness.
- Track hemoglobin and ferritin and correct deficiencies rather than only increasing cardio volume.
Visceral Fat Differs Despite Similar Body Fat
- Siim had substantially lower visceral fat (0.25 L vs 0.56 L) despite similar liver fat and body fat percent.
- Visceral fat differences can exist independent of overall body fat and affect metabolic risk.