BUFFALO, NY- August 20, 2024 – A new #editorial was #published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 15 on July 19, 2024, entitled, “Physical fitness and lifestyles associated with biological aging”. Given the growing aging population worldwide, it is crucial to develop interventional strategies that target aging itself, rather than focusing solely on organ- or disease-based medicine. The geroscience hypothesis, which suggests that delaying aging can prevent the onset of diseases, is gaining traction due to advancements in aging biomarkers, driven by improvements in both measurement techniques (e.g., omics) and analytical technologies (e.g., bioinformatics). In their editorial, researchers Takuji Kawamura, Radak Zsolt, Mitsuru Higuchi, and Kumpei Tanisawa from the Faculty of Sport Sciences at Waseda University and the Research Center for Molecular Exercise Science at Hungarian University of Sports Science, emphasize the importance of investigating the relationship between cardiorespiratory fitness (CRF) and the DNA methylation (DNAm) aging clock. Their goal is to establish fitness reference values that could help delay aging. They also discuss their recent report on the "Associations between cardiorespiratory fitness and lifestyle-related factors with DNA methylation-based aging clocks in older men: WASEDA’S Health Study." "Our study reinforces the geroscience concept that active lifestyle choices may impact quantifiable molecular biomarkers that capture biological aging.” DOI - https://doi.org/10.18632/aging.206031 Corresponding author - Takuji Kawamura - takuji3@aoni.waseda.jp Video short - https://www.youtube.com/watch?v=-j_MaL8G4eo Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206031 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, DNA methylation, epigenetic clock, physical fitness, anthropometry, blood biochemical parameters, nutritional intake About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM