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ACR Journals On Air

History of Interferon (Immunology for the Rheumatologist)

Apr 16, 2024
Dr. Mary Crow, MD, co-author of an article on interferon research, discusses its history, impact on autoimmune diseases like lupus, connections to the AIDS epidemic, and potential therapeutic applications. She also highlights exceptional patient care and research focus at the Hospital for Special Surgery, reflecting on leadership in rheumatology and the importance of embracing failures in research.
49:58

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Quick takeaways

  • Interferon research pioneers laid the groundwork for understanding interferon's therapeutic potential against viral infections.
  • Interferon dysregulation plays a dual role in host immunity and autoimmune diseases like lupus, emphasizing its impact on autoantibody production.

Deep dives

Interferon Research History: Unusual Approach to Writing a Review

Dr. Peggy Crow's manuscript delves into the history of interferon research, a unique approach to reviewing scholarly work. She highlights the contributions of early researchers like Isaac, Lindman, Nagano, and Kojima in unraveling the roles of interferon in battling viral infections.

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