Mayo Clinic Talks Lab Medicine Edition | CBC: White Blood Cell Count (WBC) (Leukocytosis, Leukopenia)
30 snips
May 2, 2024 Renowned Mayo Clinic Hematologist Ronald S. Go, M.D. and host Andy J. Herber, P.A.-C. dive into the complexities of interpreting white blood cell counts in the complete blood count, discussing various causes of abnormalities like allergies, medications, and infections. They explore the effects of GCSF on post-chemo patients, management strategies for leukopenia, and the critical thresholds of neutrophil counts, emphasizing the importance of cautious interpretation and consistent CBC monitoring for patients undergoing myelosuppressive chemotherapy.
AI Snips
Chapters
Transcript
Episode notes
Evaluating Leukocytosis
- When evaluating leukocytosis, determine which white blood cell type is elevated using absolute counts, not percentages.
- Consider non-hematologic causes like inflammation, medications, or smoking, especially for neutrophilia.
Lymphocytosis and Monocytosis
- For lymphocytosis, consider infection, chronic lymphocytic leukemia (CLL), or monoclonal B-cell lymphocytosis.
- For monocytosis, consider infection or chronic myelomonocytic leukemia (CMML), but generally, levels below 1.0 are not concerning.
Eosinophilia
- Eosinophilia is often due to medications, allergies, or parasitic infections, rarely blood cancers.
- Consider hematologic disorders if eosinophil counts exceed 1.5.