This Podcast for the Neurology Journal begins and closes with Dr. John H. Noseworthy, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interview Drs. Lisa B. Hoffman and Vahram Haroutunian about their paper on Alzheimer disease neuropathology. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Gradenigo syndrome. The podcast concludes where Dr. Thomas Wingo interviews Dr. Elliott J. Mufson for the Lesson of the Week segment. The participants had nothing to disclose.